08 Mar
Blocking effects of siRNA on VEGF expression in human colorectal cancer cells.
Posted in Gene therapy on 08.03.10 by Merlyn |
CONCLUSION: VEGF, FLT-1 and FLK-1 are associated with colorectal carcinogenesis. siRNA silencing of the VEGF gene suppresses proliferation, and induces apoptosis in HCT116 cells. The results suggest that VEGF may be a new gene therapy target for colorectal cancer.
PMID: 20205278 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
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